Eluxadoline for IBS



Eluxadoline

What Is Eluxadoline?

Eluxadoline works directly in your intestines to slow the movement of food during digestion. Eluxadoline also makes the nerves in your intestines less sensitive to stimulation.

Eluxadoline is used to treat irritable bowel syndrome when the main symptom is diarrhea.

Eluxadoline may also be used for purposes not listed in this medication guide.

You should not use eluxadoline if you have a pancreas disorder, severe liver disease, alcoholism, a blockage in your intestines, a gallbladder disorder, or if your gallbladder has been removed.

Eluxadoline may cause constipation, which could be severe or lead to hospitalization. Call your doctor at once if you have severe or ongoing constipation.

You should not use eluxadoline if you are allergic to it, or if you have:

  • severe constipation or a blockage in your intestines;
  • a history of gallbladder obstruction, or if your gallbladder has been removed;
  • digestive problems caused by a muscle valve called the sphincter of Oddi (SFINK-ter of OD-dee);
  • severe liver disease;
  • a pancreas disorder; or
  • a habit of drinking more than 3 alcoholic beverages per day.

Tell your doctor if you have ever had liver disease.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

Eluxadoline is not approved for use by anyone younger than 18 years old.

Eluxadoline Side Effects

Get emergency medical help if you havesigns of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking eluxadoline and call your doctor at once if you have:

  • new or worsening stomach pain (may be severe);
  • nausea and vomiting;
  • severe constipation;
  • constipation lasting longer than 4 days; or
  • severe pain in your upper stomach spreading to your back.

Side effects may be more likely in older adults.

Common side effects may include:

  • constipation;
  • nausea; or
  • stomach pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Eluxadoline Interactions

Avoid drinking alcohol. It may increase your risk of pancreas problems.

Avoid taking anti-diarrhea medicine such as loperamide (Imodium) without your doctor's advice. Taking loperamide long-term while you are taking eluxadoline may cause severe constipation.

Tell your doctor about all your other medicines, especially:

  • alosetron or other medications to treat irritable bowel syndrome;
  • cold or allergy medicine that contains an antihistamine (Benadryl and others);
  • opioid pain medicine;
  • medicine to treat Parkinson's disease;
  • medicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome;
  • bladder or urinary medicines--darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin; or
  • bronchodilators--aclidinium, ipratropium, tiotropium, umeclidinium.

This list is not complete. Other drugs may affect eluxadoline, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Eluxadoline Dosage

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Eluxadoline may be habit-forming.Misuse can cause addiction, overdose, or death.Selling or giving away this medicine is against the law.

Take with food.

Eluxadoline may cause constipation, which could be severe or lead to hospitalization. Call your doctor at once if you have severe or ongoing constipation.

Store at room temperature away from moisture and heat.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.Do nottake two doses at one time.

Copyright 1996-2019 Cerner Multum, Inc.






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Date: 13.12.2018, 17:13 / Views: 93142