What is prolactin?

Hormones play a very important role in the human body. In the female body, a number of hormones are noted, which work largely on reproductive function and maternity support in terms of excretion of milk and breastfeeding. Perhaps the most important hormone in this case is prolactin. Let us consider in more detail what prolactin is and what its functions are.

Prolactin: definition and function

Prolactin (otherwise - lactogenic hormone or mamotropin) - a hormone produced in the pituitary gland.

From the alternative names of this hormone, it can be revealed that prolactin affects the formation of milk in lactating and pregnant women, and during puberty of the girl he also forms the mammary glands and the ductal environment around them. It is noted that prolactin is found in other parts and organs of our body. True, his other actions are practically not studied.

Prolactin structure

Being a hormone, prolactin has a protein nature and is a polypeptide. It has about 200 amino acids linked by peptide bonds.A special element in the structure of prolactin is worth noting the presence of 3 disulfide bridges, which, with a certain impact on them, result in different types of prolactin. Pituitary cells deal with non-glycolized prolactin and excrete it.

Prolactin receptors

The action of hormones is largely due to the action of receptors. In the case of prolactin, it is customary to speak of transmembrane receptors, which act not only at the membrane level, but also in terms of interaction with various intracellular structures. The greatest accumulation of such receptors, naturally, is observed in the mammary glands.

But in addition to special female organs, prolactin receptors are also found in other organs and parts of the body. For example, they talk about the localization of such receptors in the liver, heart, spleen, lungs, kidneys and adrenal glands, organs of the reproductive system, even in the muscles of the skeleton. It is difficult to say where the prolactin receptors are absent, they are even in some parts of the central nervous system.

Disruption of prolactin

The normal content of prolactin in the body does not bother a woman, but rather contributes to the realization of maternal functions, the main of which is feeding a baby.But sometimes due to various reasons, the level of prolactin in the body varies, and this can lead to bad consequences and disorders. Of the violations of prolactin, the most critical are the increase and decrease of prolactin.

The increase in the number of prolactin in the body can be caused by pharmacological (use of drugs), surgical (associated with the transferred operations) causes, etc.

The consequences can be from minor, for example, menstrual disorders, to the most severe - violations in the mental health of a woman. There may also be a decrease in sexual desire, an increase in breast size, etc.

The reasons for reducing the content of prolactin are similar to the reasons for its increase, but they, in turn, are largely associated with the course and development of the pregnancy process. The most common disorder associated with a decrease in the content of prolactin in the body is called Sheehan syndrome.


Date: 08.10.2018, 22:41 / Views: 35374

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